41' Fernandinho drops a teasing ball behind the defence but Jesus' header goes high and wide.
40' Grealish dribbles all the way to the byline but Romeu cuts out his cross.
38' There's a brilliant run by Elyounoussi and he plays it through to Armstrong but his touch is heavy and takes him away from the goal and allows Ake to regain possession.
34' Stephens puts the ball out and goes down as he grabs at his leg. The physios rush on but it looks as if a substitution will need to be made.
33' Gundogan fires a whipped free-kick well over.
31' Jesus' shot is acrobatically blocked by Bednarek.
29' The home side are just starting to click into gear here. They have won all of their last three Premier League home games by a scoreline of 5-0.
28' Jesus' low ball in just evades the toe of Silva.
26' Sterling's curling effort goes well wide.
25' McCarthy comes for a corner and doesn't get there but Ake can't send his header goalwards and the danger is gone.
24' Grealish's delivery is low and threatening but it is cut out well by Bednarek before any damage can be done.
22' Walker's cross to the back post finds Gundogan but he just can't get high enough to send his header downwards and it goes wildly over.
20' The home side just struggling to get into a rhythm so far. The visitors have made a good start and their manager will be encouraged by what he has seen so far.
18' Sterling's ball through to Gundogan just has too much on it and is collected by McCarthy.
17' The corner goes to the back post but Fernandinho can't get enough contact on the ball to send it back across and it skims off his head for a goal-kick.
16' The hosts have a corner as a Grealish cross is blocked behind.
15' The free-kick nearly sneaks in at the far post as it goes all the way through from James Ward-Prowse.
14' The referee plays advantage but then pulls it back for a Southampton free-kick after Walker-Peters was brought down.
12' There's no doubt that Hasenhuttl's men have been the better side so far. They are threatening down the left-hand side particularly.
10' It's been a positive start for the visitors but history is not on their side in terms of Premier League games and today's opponents. City have won eight of the last nine meetings between these clubs in this competition.
9' Armstrong cuts in but his shot is intercepted before it can reach the City goal.
8' Elyounoussi tries his luck but his shot is blocked and Ederson easily catches the looping ball.
6' It'll be a home throw-in down the right after a dangerous cross from Jesus was cleared.
4' Ederson comes and claims the cross.
3' The Saints have an early corner after some good link-up play between Redmond and Walker-Peters.
2' It's the visitors who have had most of the ball so far.
1' Southampton get us underway.
The teams are making their way onto the pitch.
Saints manager Ralph Hasenhuttl also makes three alterations to his side with Bednarek, Walker-Peters and Adams starting whilst Salisu, Perraud and Djenepo drop to the bench.
City boss Pep Guardiola makes three changes to his side from their last Premier League game with Ake, Fernandinho and Sterling coming in. Foden also makes an appearance on the bench while Rodri and Laporte don’t make the squad.
SUBS: Armando Broja, Ibrahima Diallo, Fraser Forster, Moussa Djenepo, Lyanco, Romain Perraud, Mohammed Salisu, Nathan Tella, Yan Valery.
SOUTHAMPTON (4-1-4-1): Alex McCarthy; Valentino Livramento, Jack Stephens, Jan Bednarek, Kyle Walker-Peters; Oriol Romeu; Nathan Redmond, James Ward-Prowse, Mohamed Elyounoussi, Che Adams; Adam Armstrong.
SUBS: Ferran Torres, Scott Carson, Kevin De Bruyne, Phil Foden, Romeo Lavia, Riyad Mahrez, Luke Mbete, Cole Palmer, Josh Wilson-Esbrand.
MANCHESTER CITY (4-3-3): Ederson; Kyle Walker, Ruben Dias, Nathan Ake, Joao Cancelo; Ilkay Gundogan, Fernandinho, Bernardo Silva; Raheem Sterling, Gabriel Jesus, Jack Grealish.
The Saints travel north having not won any of their four Premier League games so far this season and are placed 13th in the league after drawing their last three matches. They drew 0-0 at home to West Ham in their last showing.
The Citizens head into this game off the back of a 6-3 thriller against RB Leipzig in the group stage of the Champions League, and currently sit fifth in the Premier League after a run of three straight victories. They won 1-0 away at Leicester City last time out in the league.
Hello and welcome to live coverage of this Premier League fixture between Manchester City and Southampton at the Etihad Stadium.