For the third match running Slavia Praha face a former European champion as Barcelona come to the Czech Republic.
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Liverpool are looking to end a four-match run of away defeats in the group stage, although Genk are no pushovers at home.
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Ajax are setting the pace in Group H, although Chelsea's visit could stir some painful memories of English opposition.
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Benfica are bottom of Group G and are in urgent need of a win as Lyon, who are four points better off, visit Lisbon.
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Leipzig lost at home last time out and will be keen to avoid a repeat as Group G leaders Zenit visit again.
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LOSC have lost their first two Group H games and now face a Valencia side they have never beaten in four attempts.
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Salzburg have shown fine form in front of goal on their group return, and now have the opportunity to turn the tables on Napoli.
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Shakhtar and Dinamo both have three points from their first two Group C games as they meet at Kharkiv's OSK Metalist Stadion.
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Tottenham shipped seven goals at home for the first time on Matchday 2 and now take on a buoyant Crvena zvezda.
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Fresh from a seven-goal display on Matchday 2, Bayern are looking to further strengthen their Group B position at Olympiacos.
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Manchester City have cruised through Group C to date and now take on an Atalanta side who have lost both games.
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Atlético Madrid are well placed in a tight Group D and will be aiming to inflict a third defeat on bottom side Bayer Leverkusen.
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Juventus will attempt to continue their fine record against Russian sides when Group D rivals Lokomotiv Moskva come to Turin.
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Having picked up a single point apiece from their first two matches, Galatasaray and Real Madrid need a Group A victory.
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Club Brugge's six-match unbeaten run in the UEFA Champions League will be under the microscope as Group A leaders Paris visit.
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Six forwards scored for the second game in a row on Matchday 2, including excellent budget signing Erling Braut Haaland.
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Ball recoveries have changed the complexion of the game for defenders, with Virgil van Dijk among the Matchday 2 beneficaries.
233 Hits
Serge Gnabry's 22-point haul is unlikely to be better this season, while substitutes made a sizeable impact.
234 Hits
With the group stage starting to take shape, premium goalkeepers are already proving to be value for money.
321 Hits
Ball recoveries have changed the complexion of the game for defenders, with Virgil van Dijk among the matchday 2 beneficaries.
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